Benzocaine practicals

UKOER; SFSOER; Chemistry; Outreach; Benzocaine; Organic; Esterification; Reduction; Reflux; Solvent extraction; Recrystallisation

Learning materials


Rights
Creative Commons Attribution-Non-Commercial-No Derivative Works 2.0 UK: England & Wales Licence. See: http://creativecommons.org/licenses/by-nc-nd/2.0/uk/
Description

Preparation and purification of the topical local anaesthetic benzocaine, ethyl-4-aminobenzoate, via two alternative routes: 1. via esterification of 4-aminobenzoic acid with ethanol and a strong acid catalyst; 2. via reduction of ethyl-4-nitrobenzoate using zinc dust in strong acid; - either route takes "typical" 6th form student ca. 2 - 2.5 hours to complete. Student instruction sheet and Technicians apparatus and chemicals list for each route.

Publisher
The University of Hull
Language
English
Extent
Filesize: 852KB
Identifier
hull:3855

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